MicroRNA hsa-miR-29a-3p modulates CYP2C19 in human liver cells
نویسندگان
چکیده
منابع مشابه
Suppression of CYP2C9 by MicroRNA hsa-miR-128-3p in Human Liver Cells and Association with Hepatocellular Carcinoma
Published studies have identified genetic variants, somatic mutations, and changes in gene expression profiles that are associated with hepatocellular carcinoma (HCC), particularly involving genes that encode drug metabolizing enzymes (DMEs). CYP2C9, one of the most abundant and important DMEs, is involved in the metabolism of many carcinogens and drugs and is down-regulated in HCC. To investig...
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ژورنال
عنوان ژورنال: Biochemical Pharmacology
سال: 2015
ISSN: 0006-2952
DOI: 10.1016/j.bcp.2015.08.094